SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1163173d9f19a788012d43d1f23a3f085ecf928ed47f01ef8f885a48b65b886c' 
  AND token = 'z0bz3kMNubxHtVxPLOsLwvjVxCNBOyl3+nX1Df3Ksc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}