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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cebd256621aa7c4066e8932135d141c1167fe9f3b66b77a43e63e62e0cf6016d' 
  AND token = '2ilr/FcLMJ54UqnkIEonuA88Lbj5hLnk2ORYzIZVzrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}