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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84c78e189d3131b563e841720efc34a6338b660b0966e0d4d5be5b3096f25412' 
  AND token = 'QY521dturO6vI55qr+ReChEyo3K3vLBBQBBwDklLAok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}