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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed45f75de84fc1a86c77275d7dec23a14ac4b1e085783c9f742659a86c584b72' 
  AND token = 'WwlQ9DUgLYVSBm5pOUq2K5x4BXXb1lIVdnNPCqBkpAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}