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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca3438a44fbf8f48e906fcfd4dff4b99382df4414ef31788289d0710ecb109c' 
  AND token = '64ZANJFBpu3kM3LdlF35aGd0EGobcAd6rOvlZ/NKCsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}