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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42528714faf8aa49644065aec02f02cbd4a7810a6cf76b4636b64a0bf572302f' 
  AND token = 'CDo8yH9NrBipX1YaPMWRRv1NL75sd1CgrF8ByVm0sQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}