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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '637c17c8949ae6c463158be4ca555d731268a2c9647e21cd13a6497289ad1b76' 
  AND token = 'M/R1qEPBDT0vHmWMYzNE+EbVl10KHsIEB4s3Hklyiwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}