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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526a4fa33c7cdd40aca1a4ac380d4fbf2846f87115efce383df38bd03f02f46f' 
  AND token = 't7yL+dePw/2FVDWEnQdnGSyc9xTv3YX/cG1ZQ18U9Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}