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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa1c6f470d12ff7db035137531bf93d420ff8b66743122fc104e3622ba4ab53' 
  AND token = 'kk8pvmRX4b5vmSqd/eKAx6LVPJTyi5CmLkPyMIgfs4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}