SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cbb071332c995b35ef37964bfb599e51610ad5a1747a1722db17a6c83ced50a' 
  AND token = 'dNxmkpb7hKh+1LVMuFsQ7wE5KTL8O0rrmLVKLhymaK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}