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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e91e1d4d6444b11b2311f47ba5e829216dd82469435f556c7cb061142f8b2f67' 
  AND token = '4JIPcM4aYSU96qZkuN8ohSbOTVk1sZpm6VZ4TZOhPHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}