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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf753e8dfe623c448b3c475dd980414efade6fe6f8e580be933c534c0f0123b' 
  AND token = '1sVQmq4CE42yAw7J/8ArI6VVPNgABKBaWzPPtgH7/9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}