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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458d2393b7e5bd7412d6bf61b60b2da6db6c61b69e9a104f1b52583b8935686a' 
  AND token = 'EML97N2lkRqso1TF1fLYBOO2DEJ9JmjOh2gwVynE/NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}