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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6043a09bbd3da2686b7f732600c440c3a6f75faca27e4bfb1420fa9680755841' 
  AND token = 'hRKWpHXzMZwqNHC7OfFE7QwXI/XOWzK9oPiIN/PWnno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}