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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d63538236762b9f822dd856af06e9d8ba0db21f8b410699b25cabbbe452ad22' 
  AND token = 'k+B2Wv4EeF8h6O8PHGsLWjlkfT/6cpGlTY1mx9cADq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}