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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4888171817f72b584b8d98de279036fd6853ab364ef9fa9f9b7f6e36370c247' 
  AND token = 'e0TPSVtcfD4EJuKvOvULnp9LXFqFEA4MTIYCVQeqCt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}