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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c899ae37c090a2b2e801f920e718ea4c095f2eb8f8f53c058bf8d5cea329579' 
  AND token = 'mL0ICEbQQEe/G7Kp+WtxvEdoPTy5fSdznhpp5g5MTZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}