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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c552fa39566adaa7007f7d241b76e8f989c5a250d24e770314da6efdf65147' 
  AND token = 'n5V0USA05jnwntRWMCVFCMzQ8qrcIfbeLmhiSNzeTCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}