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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '057b076e84d256e37e3821d2653383c10a4cd8f21ea4a880fd5942249e7e7dc2' 
  AND token = 'S1KTk3YkGRm6mR/r6cW1zGxe7O+ciB/Mo2lphw2dpmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}