SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e876a401a7ae8bdfbda31706ea805b677e25c81e2c1da0f3335505fd35901ad8' 
  AND token = 'AEKtRs36K46S2KsD1MNfT/btG4hvQWeNYalyuiNOwVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}