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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f8d0408ebab961ad1858c49fac9b26d1d561688af4706f8669742df6870171' 
  AND token = 'wHQtET6Ke1w7WcYy4IpIN9/CyWPSxZ0uJoCHFKcqCbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}