SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eeacc2f6405ad75bb37241de3834267e85ad38bd1c0328888a4ee2c5314dea8' 
  AND token = 'EH4Bmng+fnc/6EfE9va8HzU++GW21lPlBMAU6DaHHXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}