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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281a00355b283fe294f83b88970f97c5f0bf2176946f664b0313a7c27e5fc2d6' 
  AND token = 'EFvJibVCT3XaAczRwUfoWnfAQQxIW1bt0jguEJoJdqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}