SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adc63bd443c9654732b0e3c6f651f575e6e0dc3460161039a0042b166ca1d3c' 
  AND token = 'sFz5mzOapI6srL+9H/43aMesqpM38fbZ/HoHn50kjIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}