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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4325417326807bd08281c16c86d68406f4cf0bbef89e48277cb31326f2db4eb6' 
  AND token = '1ErovuEYNRuK7gyNlaGGrq5VZ3maUcwA31GR6i1/wNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}