SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc2bb7f7a13dfd73b6628e8a272bd4d66116163394eb02c663c69a4e5bfa282' 
  AND token = 'SCVTEV2nagWtGvZI3UwdXs6KYui2nOPO+yNiW8d+Nac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}