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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1555edf5012f6d8a09fa6490454bc5596621e0ee40ee7d5e552f6832fc87f271' 
  AND token = 'IpDwEZE6/G8LwoWqNUxE/ei2YHQxeIWPun3u8DnqYA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}