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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a296da08e750f1bb743a429403a396aaeab837cdd3c8bc3770e369a79180d01' 
  AND token = 'BPX6BmGsxDqp6Z0E0H4dk0qLe5SOo1oSbzJOemhmFtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}