SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad5808a192fd2c40815bf3da8ae5deadb51eb9cac63af0404e9db393b701788' 
  AND token = 'LTILeIhDHzzstkqgCo1H7FGVx94rJ5iLiQoUdZy3DRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}