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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0edeb3a7ea84341b85431cf5645d1a3ed85a1a5ddb567ec4119595851deac396' 
  AND token = 'HdklWLAdo8Q9et5YCuUQdZyVo6NyeXFVrM0CrBJFuCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}