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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7e00740452ca03eecc8589275065ab9a4fd3240aebab721b549644c927dce5' 
  AND token = 'Edmtw1Xs0YmWKwR2NdIF8otDHA7+msYee3gI3Ie0f1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}