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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e927d27df3c849b5c8385af1375bcc028e7c25c3bd50a9f8ef22447ffe969e' 
  AND token = 'vENvsmTP5zSpDSLMTys6E+iLdqRKeSKaF0IQLhD7zVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}