SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fcef5599db43f8e4540c051f519cdd79244f11f71e3caa09fb4cb58ccb19090' 
  AND token = 'hRecrHPPCV+nHN6vKA+XcJTVEsw5WKhWi7vNtUIPwYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}