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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8500ee01d8cbb59b1f23aca0e2cb57ad0438479acbcd6a6f8b78d50706ef3289' 
  AND token = 'Q1iUq/jjDzQy6rBMu2rK2VnFZknlS5TmBCFT/NiQuug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}