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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '184b41b3b1377432405ecf90e197c65550b20a5024eb5ba2e3ed5f22e108c318' 
  AND token = 'oa4FlSA+UMrrwarqQoiyMcdeY3TPad0ZdaGCRGDmOMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}