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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5680ca67eca2a5d04497ffc67cf1e5a76e2fe98b105265581b04027cf8cc5751' 
  AND token = 'IaYnNeQABVCEPzgWMQLIiGWMOXOxdGpHuY0Rs52c12M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}