SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a78767738b9c9279d04c5b5dcafd55f182a447880a4ad43f349d2dfb1d0900' 
  AND token = 'q3D4Zp8YRtqrsZHgJNAplzhuyAi92rgq3c7ObMIh3qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}