SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4b4fc4e984f3a002067e34a72db00d38c009b184c48214276c488a5628d8a0' 
  AND token = 'c4rxfBLBJBYaSst+Pz70qmaIbT9vD6sPPhUKCVJxNxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}