SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da950e325ead24e58b3b16094a67b1d85770f1c48221b6690259e5ccad663209' 
  AND token = 'fFc/0SGMxp9tmbBKcuuM2vrztczGgm6jVS3JX7x2txw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}