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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49f5eb25fb415ce6b72efaed684790ea72f68aaee20c48f388a4c8433475549' 
  AND token = '4PXOG+UIC03aOTJ6eOL4JszoDAG9Heah59uxd/iNWRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}