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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fa297e3749338ee3411f375819b6fcda76157e541f50af93bdf96d51eead098' 
  AND token = 'Khz2sk0S+i4yOJ3E/ug3ES1D52nnvdZ4h2X2yNK78c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}