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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff45eb460b86a13d34d2f9136660d77ccd6de7b075b29c4edc8b4f08ad9a34f' 
  AND token = 'AFTTfR7dzgpBxuv+fqwlAOYrSKpyot6bIBpzO8nwFAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}