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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80964733bfc21a7c59d01fbb786f7d09644c7d2265358c60278095652355806f' 
  AND token = '0wYn5CvCh7jNyAlXMyKDZ14ZhSWFvSP7t6MGM7w6VyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}