SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b56368efeb5675ee557287fc821a212ab1b5a606a3c0ecc8dc0e1dd38b734209' 
  AND token = 'd/CmYkEfcOLLy7wrlQNxy8sCOxF1RESziGi7lO4PHIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}