SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d081d5e0047d7d41c532b0f011b559118d95f58b0b96cbd0c0070c3a425119f' 
  AND token = 'IlkDEkny05ElMIVbKegwSsEqDlH1O35LILEGZy2L9lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}