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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34bcc24ac1b837e55cbdc7366fed2eb235505376c83a7cc4ccec4542f04eed3d' 
  AND token = 'GkClfLUPxZJhnSZT3+VxLzcEag/SJ26D63C1TMIYENs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}