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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa5b73bdd333f61e85266ec5c18b0e3e41ce92d7a9c0b22b26c21466698dfd4' 
  AND token = 'F7JQOYboe0SNyhEY4vmdQNUa3aj/TeXLGufhDFtWHUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}