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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e93f509418c9c2369e017a549645d066b4d1e9b2a462e4651f9d512aa1aeb2' 
  AND token = 'TmiyDH3s/DmP4jr3F3tRg2xds2D0GizOFIgr2pDA4nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}