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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484f6ced1a834b02525e9664f9f1c6e0fbb455c2f221697ec196601d60d35049' 
  AND token = 'T3tux85qYw13DZWKx1GjPOFJae8mkAEk7jcklgWoj4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}