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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bd45f58a9473f21d8cb50284e5b713cd8dc08b5d185c1fcdd819085384e11f2' 
  AND token = '43yfUCK71mTrudJGUoECWKsSri7SbE4CmDr8Xn12T10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}